Predicting Aggressive Prostate Cancer Through Change In PSA Levels Over Time
1/17/2013
Measurements taken over time of prostate specific antigen, the most commonly used screening test for prostate cancer in men, improve the accuracy of aggressive prostate cancer detection when compared to a single measurement of PSA, according to a Kaiser Permanente study published in the British Journal of Urology International...
Recent studies have demonstrated that molecular-targeted agents, such as epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI), may prolong survival of selected patients based on tumor biomarkers. The presence of mutation in the EGFR gene is known as a predictive marker for the response to treatment...
In Non-Small-Cell Lung Cancer, Patients With EGFR Exon 20 Insertions Have Poorer Prognosis
1/17/2013
Exon 20 insertions are the third most common family of epidermal growth factor receptor (EGFR) mutations found in non-small-cell lung cancer (NSCLC). Little is known about cancers harboring these mutations aside from their lack of response to EGFR tyrosine kinase inhibitors, impairing the development of effective targeted therapies...
For patients with medically operable clinical stage I non-small-cell lung cancer (NSCLC), lobectomy or pneumonectomy is the standard approach. For patients with medically inoperable stage I NSCLC, stereotactic body radiotherapy (SBRT) has become a standard of care...
Researchers at The University of Texas at Austin have developed a menu of 61 new strains of genetically engineered bacteria that may improve the efficacy of vaccines for diseases such as flu, pertussis, cholera and HPV. The strains of E...
Gene Sequencing Program Gives Researchers New Leads To Improve Cancer Treatment
1/17/2013
It started with a 44-year-old woman with solitary fibrous tumor, a rare cancer seen in only a few hundred people each year. By looking at the entire DNA from this one patient's tumor, researchers have found a genetic anomaly that provides an important clue to improving how this cancer is diagnosed and treated...
Researchers at The University of Texas at Austin have developed a menu of 61 new strains of genetically engineered bacteria that may improve the efficacy of vaccines for diseases such as flu, pertussis, cholera and HPV. The strains of E...
Pill-Camera Promising Alternative To Endoscopy For Cancer Diagnosis
1/16/2013
Researchers in the US have developed a high-tech camera you can swallow that takes detailed images of the insides of the gullet (esophagus) and stomach...
A New Way Found To Boost Common Cancer Drugs
1/16/2013
Shutting down a specific pathway in cancer cells appears to improve the ability of common drugs to wipe those cells out, according to new research from scientists at Fox Chase Cancer Center, published in the January issue of Cancer Discovery...
Novel Role Of The NEDD9 Gene Discovered In Early Stages Of Breast Cancer
1/16/2013
Breast cancer is the second leading cause of cancer deaths among women in the United States. Many of these deaths occur when there is an initial diagnosis of invasive or metastatic disease. A protein called NEDD9 - which regulates cell migration, division and survival - has been linked to tumor invasion and metastasis in a variety of cancers...