End-Of-Life Care For Elderly Often Too Aggressive
2/06/2013
There has been an increase in hospice usage and ICU utilization over the last ten years among elderly patients, researchers from Brown University reported in JAMA. The authors added that with more late health care transitions, repeat hospitalizations, does such aggressive care really represent what patients and their loved ones really want? Probably not...
Generic Version Of Cancer Drug Doxil Approved By FDA
2/06/2013
The U.S. Food and Drug Administration has just approved a generic version of the cancer drug Doxil (doxorubicin hydrochloride liposome injection). There is currently a serious shortage of the drug Doxil, and the decision by the FDA to allow a generic version on the market will help the thousands of people in need of the drug to survive...
Generic Version Of Cancer Drug Doxil Approved By FDA
2/06/2013
The U.S. Food and Drug Administration has just approved a generic version of the cancer drug Doxil (doxorubicin hydrochloride liposome injection). There is currently a serious shortage of the drug Doxil, and the decision by the FDA to allow a generic version on the market will help the thousands of people in need of the drug to survive...
Some Cancer Mutations Slow Tumor Growth
2/06/2013
Surprising result suggests that enhancing these mutations' impact could offer a new way to treat cancer. A typical cancer cell has thousands of mutations scattered throughout its genome and hundreds of mutated genes. However, only a handful of those genes, known as drivers, are responsible for cancerous traits such as uncontrolled growth...
University of Pittsburgh Cancer Institute (UPCI) researchers have uncovered a technique to halt the growth of cancer cells, a discovery that led them to a potential new anti-cancer therapy. When deprived of a key protein, some cancer cells are unable to properly divide, a finding described in the cover story of the February issue of the Journal of Cell Science...
On World Cancer Day, UICC and International Agency for Research on Cancer (IARC) reveal real-life impact of achieving goal. The Union for International Cancer Control (UICC) and the International Agency for Research on Cancer (IARC) today announced that 1...
Researchers Hail Gene Breakthrough In Bid To Prevent Spinal Tumours
2/06/2013
Medical researchers have discovered a gene that is responsible for causing an inherited form of tumour known as spinal meningioma. Meningiomas are the commonest form of tumour affecting the brain and spine and are common in people who are affected by the genetic disorder Neurofibromatosis 2 (NF2)...
The Immune System Can Use Melanoma's Own Proteins To Kill Off Cancer Cells
2/06/2013
Though a small group of proteins, the family called Ras controls a large number of cellular functions, including cell growth, differentiation, and survival. And because the protein has a hand in cellular division, mutated Ras, which can be detected in one-third of all tumors, contributes to many human cancers by allowing for the rapid growth of diseased cells. Now Prof...
Research Aims Knockout Punch At Hepatitis B In A Fight To The Finish
2/06/2013
In research published in the journal PLOS Pathogens, Saint Louis University investigators together with collaborators from the University of Missouri and the University of Pittsburgh report a breakthrough in the pursuit of new hepatitis B drugs that could help cure the virus...
New Light Shed On Gene Organization And Regulation By Paired Genes In Stem Cells
2/06/2013
Whitehead Institute researchers have determined that DNA transcription, the process that produces messenger RNA (mRNA) templates used in protein production, also runs in the opposite direction along the DNA to create corresponding long noncoding RNAs (lncRNAs). Moreover, the mRNAs and lncRNAs are transcribed coordinately as stem cells differentiate into other cell types...