Novel Designed Molecules Could Stop Colon Cancer Metastasis
2/15/2013
A Basque research consortium has managed to stop the development of colon cancer and its liver metastasis in an experimental model using mice. This breakthrough, which could open new avenues for the future treatment of these pathologies, has been achieved by creating molecules that interfere with the tumour cells adhering to other cells in the body...
Copper Depletion Therapy Keeps High-Risk Triple-Negative Breast Cancer At Bay
2/15/2013
An anti-copper drug compound that disables the ability of bone marrow cells from setting up a "home" in organs to receive and nurture migrating cancer tumor cells has shown surprising benefit in one of the most difficult-to-treat forms of cancer -- high-risk triple-negative breast cancer. The median survival for metastatic triple-negative breast cancer patients is historically nine months...
Comparison Of Tube And IV Feeding In Malnourished Pediatric Cancer Patients
2/15/2013
About 60 percent of pediatric cancer patients experience malnourishment during treatment. At that point, patients and families have a choice: tube feeding or IV nutrition supplement...
Growth Of Cancerous Liver Tumors Suppressed By Key Molecule
2/15/2013
A molecule already implicated in a number of diverse cellular functions can suppress the growth of tumors in the liver, a Mayo Clinic Cancer Center study has found. Its name is IQGAP1, and when the molecule is active in the cells that surround a tumor cell, this "tumor microenvironment" becomes less hospitable to cancer growth. When the molecule is deficient, cancer thrives...
Gene Discovered That Suppresses Herpesviruses
2/15/2013
Kaposi's sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) hide within the worldwide human population. While dormant in the vast majority of those infected, these active herpesviruses can develop into several forms of cancer...
Bisphosphonate Treatment May Protect Bone From The Negative Effects Of Emerging Cancer Drugs
2/15/2013
Cancer drugs should kill tumors, not encourage their spread. But new evidence suggests that an otherwise promising class of drugs may actually increase the risk of tumors spreading to bone, according to researchers at Washington University School of Medicine in St. Louis. The drugs, IAP antagonists, block survival signals that many cancer cells rely on to stay alive...
Protein central to cancer stem cell formation provides new potential target Researchers have identified a pivotal protein in a cellular transformation that makes a cancer cell more resistant to treatment and more capable of growing and spreading, making it an inviting new target for drug development...
Anti-Copper Drug Might Prevent Organ Metastasis in Triple-Negative Breast Cancer
2/15/2013
An anti-copper drug compound that disables the ability of bone marrow cells from setting up a "home" in organs to receive and nurture migrating cancer tumor cells has shown surprising benefit in one of the most difficult-to-treat forms of cancer -- high-risk triple-negative breast cancer. The median survival for metastatic triple-negative breast cancer patients is historically nine months...
Mothers Cope With Child's Cancer Diagnosis With The Help Of Problem-Solving Training
2/15/2013
A multi-site clinical trial including the University of Colorado Cancer Center shows that the benefit of Bright IDEAS problem-solving skills training goes beyond teaching parents to navigate the complex medical, educational, and other systems that accompany a child's diagnosis of cancer - the training also leads to durable reduction in mothers' levels of anxiety and symptoms of...
Lung Cancer To Overtake Breast Cancer Among Women In Europe
2/14/2013
Within the next decade lung cancer is predicted to be the main cause of cancer deaths in European women, according to a recent study published in the journal Annals of Oncology. Lung cancer has already become the main cause of cancer death among women in the UK and Poland, overtaking breast cancer...