Visceral Fat Causally Linked To Intestinal Cancer
3/06/2013
Loss of fat by surgical removal or a calorierestricted diet reduced likelihood of developing intestinal tumors. Differences were found between male and female mice. Study emphasizes the need for strategies to reduce visceral fat...
Expression of most microRNAs was similar between the two conditions. A small number were differentially expressed. These microRNAs could be biomarkers for early diagnosis of progression...
Many Children With Retinoblastoma May Safely Forego Adjuvant Chemotherapy
3/06/2013
New results from a prospective clinical trial conducted in France show that children with low-risk retinoblastoma do not need postoperative (adjuvant) chemotherapy to prevent disease recurrence or metastasis; the results also suggest that certain patients with intermediate-risk disease can receive less aggressive adjuvant treatment, or perhaps forego it altogether...
Colonoscopy May Reduce Advanced Cancer Risk By 70%
3/06/2013
Colonoscopy screening reduces the risk of advanced colorectal cancer by about 70% in average-risk adults. The finding came from a new study led by a researcher at the Perelman School of Medicine at the University of Pennsylvania and was published in the journal Annals of Internal Medicine...
Visceral Fat Causally Linked To Intestinal Cancer
3/06/2013
Loss of fat by surgical removal or a calorierestricted diet reduced likelihood of developing intestinal tumors. Differences were found between male and female mice. Study emphasizes the need for strategies to reduce visceral fat...
Expression of most microRNAs was similar between the two conditions. A small number were differentially expressed. These microRNAs could be biomarkers for early diagnosis of progression...
Many Children With Retinoblastoma May Safely Forego Adjuvant Chemotherapy
3/06/2013
New results from a prospective clinical trial conducted in France show that children with low-risk retinoblastoma do not need postoperative (adjuvant) chemotherapy to prevent disease recurrence or metastasis; the results also suggest that certain patients with intermediate-risk disease can receive less aggressive adjuvant treatment, or perhaps forego it altogether...
Gene Related To Obesity Increases Risk For Melanoma
3/05/2013
The research shows that people with particular variations in a stretch of DNA within the FTO gene, called intron 8, could be at greater risk of developing melanoma. Variations in a different part of the FTO gene, called intron 1, are already known to be the most important genetic risk factor for obesity and overeating...
Research Offers Patients Hope For New Treatments For An Aggressive And Common Lymphoma
3/05/2013
The powerful master regulatory transcription factor called Bcl6 is key to the survival of a majority of aggressive lymphomas, which arise from the B-cells of the immune system. The protein has long been considered too complex to target with a drug since it is also crucial to the healthy functioning of many immune cells in the body, not just B cells gone bad...
News From The Annals Of Internal Medicine: March 5, 2013
3/05/2013
A special supplement on patient safety strategies will be published with the March 5 issue. In addition to the 10 articles included in the supplement, Annals of Internal Medicine also will publish a special five-page graphic narrative on the topic of medical errors. 1...