Hemophilia Mystery Solved
3/10/2013

An Australian researcher has found the third and final missing piece in the genetic puzzle of an unusual form of hemophilia, more than 20 year after he discovered the first two pieces. Professor Merlin Crossley, of the University of New South Wales, and his international team studied the blood-clotting disorder, hemophilia B Leyden, which is unusual because symptoms improve after puberty...

Bathing Abdomen In Chemotherapy Gives Ovarian Cancer Patients Better Chance Of Survival
3/09/2013

More Women Should Receive Intraperitoneal Treatment, Suggests 10-Year Follow-up Patients with advanced ovarian cancer who undergo intensive treatment with chemotherapy that bathes the abdomen are significantly more likely to live longer than those who receive standard intravenous (IV) chemotherapy, according to a study that analyzed long-term follow-up from two landmark Gyne...

Bathing Abdomen In Chemotherapy Gives Ovarian Cancer Patients Better Chance Of Survival
3/09/2013

More Women Should Receive Intraperitoneal Treatment, Suggests 10-Year Follow-up Patients with advanced ovarian cancer who undergo intensive treatment with chemotherapy that bathes the abdomen are significantly more likely to live longer than those who receive standard intravenous (IV) chemotherapy, according to a study that analyzed long-term follow-up from two landmark Gyne...

Lung Tumors Eradicated In A Pre-Clinical Mouse Model
3/09/2013

The study, led by the Vall d'Hebron Institute of Oncology, has managed to eliminate mouse lung tumors by inhibiting Myc, a protein that plays a key role in the development of many different tumors Previous studies had already shown that Myc was a key protein in tumour development and had established how to inhibit Myc through gene therapy This protein is involve...

Cancer Immune Therapy AV0113 Receives Orphan Drug Designation
3/09/2013

The European Medicines Agency recently awarded the Austrian biotech company Activartis an Orphan Drug Designation for its innovative Cancer Immune Therapy AV0113. The Orphan Drug Designation applies specifically to the use of AV0113 for the treatment of glioma, a type of brain tumour, which afflicts around one in 10.000 people in the EU...

Lung Tumors Eradicated In A Pre-Clinical Mouse Model
3/09/2013

The study, led by the Vall d'Hebron Institute of Oncology, has managed to eliminate mouse lung tumors by inhibiting Myc, a protein that plays a key role in the development of many different tumors Previous studies had already shown that Myc was a key protein in tumour development and had established how to inhibit Myc through gene therapy This protein is involve...

Cancer Immune Therapy AV0113 Receives Orphan Drug Designation
3/09/2013

The European Medicines Agency recently awarded the Austrian biotech company Activartis an Orphan Drug Designation for its innovative Cancer Immune Therapy AV0113. The Orphan Drug Designation applies specifically to the use of AV0113 for the treatment of glioma, a type of brain tumour, which afflicts around one in 10.000 people in the EU...

Ovarian Cancer May Arise From Stem-Like Cells
3/08/2013

Scientists have discovered that the ovary contains a group of cells similar to stem cells that can mutate to form tumors. In a study of mouse ovaries, they found they could coax the stem-like cells to become cancerous by switching off two tumor-suppressing genes. The study is likely to make a significant contribution to what we know about ovarian cancer...

Ovarian Cancer May Arise From Stem-Like Cells
3/08/2013

Scientists have discovered that the ovary contains a group of cells similar to stem cells that can mutate to form tumors. In a study of mouse ovaries, they found they could coax the stem-like cells to become cancerous by switching off two tumor-suppressing genes. The study is likely to make a significant contribution to what we know about ovarian cancer...

Getting To The Root Of Aggressive Ovarian Cancer
3/08/2013

Cornell University researchers have discovered a likely origin of epithelial ovarian cancer (ovarian carcinoma), the fifth leading cause of cancer death among women in the United States. Pinpointing where this cancer originates has been difficult because 70 percent of patients are in advanced stages of disease by the time it is detected...