Intensity Modulated Radiotherapy Reduces Side Effects In Patients With Early Breast Cancer
4/23/2013
Intensity modulated radiotherapy (IMRT) gives better results than standard radiotherapy in patients with early breast cancer, according to results from a randomised trial presented today (Sunday) to the 2nd Forum of the European Society for Radiotherapy and Oncology (ESTRO)...
Hope For New Tailor-Made Anti-Cancer Agents
4/23/2013
Scientists at the Walter and Eliza Hall Institute and their collaborators have tailor-made a new chemical compound that blocks a protein that has been linked to poor responses to treatment in cancer patients. The development of the compound, called WEHI-539, is an important step towards the design of a potential new anti-cancer agent...
A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer. The analysis, conducted by researchers at Columbia University Medical Center, also identified hundreds of potential drug targets that could cut off a tumor's fuel supply or interfere with its ability to synthesize essential building blocks...
Ludwig researchers Arshad Desai and Christopher Campbell, a post-doctoral fellow in his laboratory, were conducting an experiment to parse the molecular details of cell division about three years ago, when they engineered a mutant yeast cell as a control that, in theory, had no chance of surviving. Apparently unaware of this, the mutant thrived...
New Potential Target For Cancer Therapy Identified
4/23/2013
Researchers at UT Southwestern Medical Center have found that alternative splicing - a process that allows a single gene to code for multiple proteins - appears to be a new potential target for anti-telomerase cancer therapy. The enzyme telomerase is overexpressed in almost all cancer cells, and previous research efforts have failed to identify good telomerase inhibitors. The study by Dr...
Proliferation Of Two Breast Cancer Lines Stymied By Low-Dose Aspirin
4/23/2013
Regular use of low-dose aspirin may prevent the progression of breast cancer, according to results of a study by researchers at the Veterans Affairs Medical Center in Kansas City, Mo., and the University of Kansas Medical Center. The study found that aspirin slowed the growth of breast cancer cell lines in the lab and significantly reduced the growth of tumors in mice...
Research Suggests 'Chemo Brain' May Involve Neurophysiological Change
4/23/2013
For many years, breast cancer patients have reported experiencing difficulties with memory, concentration and other cognitive functions following cancer treatment. Whether this mental "fogginess" is psychosomatic or reflects underlying changes in brain function has been a bone of contention among scientists and physicians. Now, a new study led by Dr...
Tumor Growth In Breast Cancer And Angiosarcoma Inhibited By Novel Monoclonal Antibody
4/23/2013
A monoclonal antibody targeting a protein known as SFPR2 has been shown by researchers at the University of North Carolina to inhibit tumor growth in pre-clinical models of breast cancer and angiosarcoma...
Same Protein That Fires Up Cancer-Promoting Erk Also Blocks Its Activation
4/23/2013
A protein which is intimately involved in cancer-promoting cell signaling also keeps a key component of the signaling pathway tied down and inactive, a team led by scientists from The University of Texas MD Anderson Cancer Center reports in Nature Structural Molecular Biology...
Dispelling The Myth That Smoking From Hookah Is A Harmless Alternative To Cigarettes
4/23/2013
Smoking tobacco through a hookah is a pastime gaining popularity among the college crowd, but many of them mistakenly believe that using the fragrant water pipe is less harmful than smoking cigarettes. In a new study at UC San Francisco, researchers measuring chemicals in the blood and urine concluded that hookah smoke contains a different - but still harmful - mix of toxins...