Molecular Messages Decoded That Tell Prostate And Breast Cancers To Spread
5/02/2013
Cancer cells are wily, well-traveled adversaries, constantly side-stepping treatments to stop their spread. But for the first time, scientists at the University of Michigan have decoded the molecular chatter that ramps certain cancer cells into overdrive and can cause tumors to metastasize throughout the body...
Scientists Decode "Molecular Chatter" That Makes Cancer Cells Spread
5/02/2013
For the first time, scientists in the US have decoded the "molecular chatter" that makes cancer cells more aggressive and more likely to travel and set up tumors in other parts of the body (metastasize). The discovery came about as a result of bringing together specialists in cancer development with specialists in wound healing...
Efficacy Of Tumor-Killing Enzyme Improved By Protein
5/02/2013
Scientists have devised a method for delivering tumor cell-killing enzymes in a way that protects the enzyme until it can do its work inside the cell. In their study in mBio®, the online open-access journal of the American Society for Microbiology, researchers assembled microscopic protein packages that can deliver an enzyme called PEIII to the insides of cells...
Experimental Drug Inhibits Growth In All Stages Of Common Kidney Cancer
5/02/2013
Researchers at Mayo Clinic's campus in Florida have discovered a protein that is overly active in every human sample of kidney cancer they examined. They also found that an experimental drug designed to block the protein's activity significantly reduced tumor growth in animals when used alone. Combining it with another drug already used to treat the cancer improved the effectiveness of both...
Study Confirms That VEGF Is Not A Path Forward To Tackling Advanced Prostate Cancer
5/01/2013
The well-studied protein VEGF does not appear to have any prognostic or predictive value for men with locally advanced prostate cancer, researchers from the Department of Radiation Oncology at Thomas Jefferson University Hospital and other institutions found in a retrospective study published online in the journal BMC Radiation Oncology...
Discovery Of Markers Related To Ovarian Cancer Survival And Recurrence
5/01/2013
Researchers at the University of Illinois have identified biomarkers that can be used to determine ovarian cancer survival and recurrence, and have shown how these biomarkers interact with each other to affect these outcomes. Their findings appear in the journal PLOS ONE...
New Genetic Sequencing Lab Creates "Tipping Point" For Personalised Cancer Care In UK
5/01/2013
A new genetic profiling laboratory that will pioneer a quick and cost-effective new tumour test will give doctors a better chance of identifying the right treatment for UK cancer patients and increase access to clinical trials for the latest therapies...
Oxford BioTherapeutics (OBT) and Boehringer Ingelheim(BI) have announced a new alliance focused on the discovery of novel cancer antibody targets that OBT will identify with the help of its OGAP(R) discovery platform...
Mapping Of Cancer Cell Fuel Pumps Paves The Way For New Drugs
5/01/2013
For the first time, researchers at Karolinska Institutet in Sweden have managed to obtain detailed images of the way in which the transport protein GLUT transports sugars into cells...
Scientists Discover How A Protein Finds Its Way
5/01/2013
Proteins, the workhorses of the body, can have more than one function, but they often need to be very specific in their action or they create cellular havoc, possibly leading to disease. Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered how an enzyme co-factor can bestow specificity on a class of proteins with otherwise nonspecific biochemical activity...