Diabetes Drug Makes Lung Cancer Vulnerable To Radiotherapy
5/03/2013
THE DIABETES drug metformin slows the growth of lung cancer cells and makes them more likely to be killed by radiotherapy, according to a study published in the British Journal of Cancer this week...
How Some Cancers "Poison The Soil" To Block Metastasis
5/03/2013
Research Shows Therapeutic Proteins Could Offer Much Needed Treatment Strategy for Metastatic Cancer Cancer spread or metastasis can strike unprecedented fear in the minds of cancer patients...
Computer Scientists Assemble The Most Complete Genetic Profile Yet Of Acute Myeloid Leukemia
5/03/2013
Powerful data-sifting algorithms developed by computer scientists at Brown University are helping to untangle the profoundly complex genetics of cancer. In a study reported today in the New England Journal of Medicine, researchers from Washington University in St...
Mathematics, Nature, Help Researchers Understand The Immune System And Its Role In Cancer
5/03/2013
Can the patterns in tree branches or the meandering bends in a river provide clues that could lead to better cancer therapies? According to a new study from Virginia Commonwealth University Massey Cancer Center, these self-similar, repeating patterns in nature known as fractals help scientists better understand how the immune system is organized and may one day be used to help ...
The Search For Therapeutic Synergy In Primary Effusion Lymphoma
5/03/2013
Primary effusion lymphoma (PEL) is a rare, fatal form of aggressive B-cell lymphoma caused by Kaposi's sarcoma-associated herpesvirus (KSHV). The disease most commonly occurs in immunocompromised patients, such as those with HIV and the elderly. Because current treatment options are not effective, there is a great need for new PEL therapies...
Mutations Discovered That May Affect Treatment Of Patients With Endometrial Cancer
5/03/2013
A study from the Cancer Genome Atlas Research Network, led by the National Cancer Institute and the National Human Genome Research Institute, report that mutations discovered in endometrial cancer genes may directly impact treatment plans for women with aggressive endometrial cancer, as well as the classification of endometrial cancer tumors. The study was published in the journal Nature...
Endometrial Cancer Treatment May Be Reshaped By Genomics
5/03/2013
The most in-depth look yet at endometrial cancer shows that adding genomics-based testing to the standard diagnostic workup could change the recommended course of treatment for some women. The new research, involving nearly 400 women with endometrial cancer, is published in the journal Nature...
A new study from investigators at the Benson-Henry Institute for Mind/Body Medicine at Massachusetts General Hospital (MGH) and Beth Israel Deaconess Medical Center (BIDMC) finds that elicitation of the relaxation response - a physiologic state of deep rest induced by practices such as meditation, yoga, deep breathing and prayer - produces immediate changes in the expression of...
The Up And Down Side Of 'Traffic' In Our Cells
5/03/2013
A mechanism that permits essential substances to enter our cells while at the same time removing from them harmful components also has a "down side." This negative aspect prevents vital drugs, such as anti-cancer drugs, from achieving their designed functions, while also enabling bacterial cells to develop resistance to penetration of antibiotics...
In Oropharyngeal Squamous Cell Carcinoma, HPV Leaves Its Mark
5/03/2013
Oropharyngeal squamous cell carcinoma (OPSCC) is a form of cancer that affects the cells lining the middle part of the throat, including the soft palate, the base of the tongue, the tonsils, and the pharynx...