New Mathematical Modeling Approach To Analyzing Colorectal Cancer Clinical Trial Data
5/11/2013

Certaraâ„¢, a leading provider of software and scientific consulting services to improve productivity and decision-making from drug discovery through drug development, announced that its Pharsight Consulting Services has developed a mathematical model of tumor growth inhibition, which when combined with baseline prognostic factors, predicts treatment effect with bevacizumab...

Clues To New Treatments For A Harmful Blood Clotting Disorder
5/11/2013

A gene associated with both protection against bacterial infection and excessive blood clotting could offer new insights into treatment strategies for deep-vein thrombosis - the formation of a harmful clot in a deep vein...

Tumors Invading The Aorta Successfully Removed Via Thoracic Endografts
5/10/2013

Tumors have the potential to grow locally and invade neighboring organs. Some chest tumors may invade one of the great vessels of the body, the aorta. Surgical removal of these tumors is very challenging and necessitates the support of a heart-lung machine. Therefore there is an increased risk of complication and death...

Analysis Shows Cancer Biorepository Speeds Clinical Trials, Drug Development
5/10/2013

Researchers at Moffitt Cancer Center say identifying and selecting participants for phase II cancer clinical trials from a centralized warehouse of patient-donated biological data expedites participant accrual, reduces trial size, saves money, and may speed test drugs through the drug development pipeline...

Fun And Friends Help Ease The Pain Of Breast Cancer
5/10/2013

Kaiser Permanente study among the first to examine how social relationships influence quality of life in breast cancer patients Breast cancer patients who say they have people to have a good time, or "positive social interactions," with are better able to deal with pain and other physical symptoms, according to a new Kaiser Permanente study published this week in Breast Can...

Quality Of Life Better For Breast Cancer Patients Who Have Fun And Friends
5/10/2013

Breast cancer patients who say they have people with whom they have a good time, or have "positive social interactions" with, are better able to deal with pain and other physical symptoms, according to a new Kaiser Permanente study published in Breast Cancer Research and Treatment...

Prostate Cancer Spread May Be Driven By Amplification Of A Stat5 Gene Which Produces Excess Oncogenic Protein
5/10/2013

An international group of investigators, led by researchers at Thomas Jefferson University's Kimmel Cancer Center, have solved the mystery of why a substantial percentage of castrate-resistant metastatic prostate cancer cells contain abnormally high levels of the pro-growth protein Stat5...

GSK, Merck Cut Price Of HPV Vaccine In Poor Countries
5/10/2013

A new all-time low price for human papillomavirus (HPV) vaccines will now help guarantee that millions of girls in poor countries are protected against cervical cancer. This will be made possible by the GAVI alliance (the Global Alliance for Vaccines and Immunization) - a public-private partnership that aims to save children's lives by funding vaccines in the world's 70 poorest nations...

Potential Therapeutic Target Discovered For Cushing's Disease
5/10/2013

Scientists at the Salk Institute for Biological Studies have identified a protein that drives the formation of pituitary tumors in Cushing's disease, a development that may give clinicians a therapeutic target to treat this potentially life-threatening disorder...

Bladder Cancer Could Reoccur Despite Bladder Removal
5/10/2013

Patients with advanced bladder cancers that are surgically removed might need additional therapy to prevent recurrence in certain situations, a new UT Southwestern Medical Center study suggests...