Best Treatment For High-Risk Low-Grade Glioma Is Still Radiotherapy
5/31/2013
In a large, international, randomized trial, initial radiotherapy was compared to temozolomide chemotherapy. A statistically significant difference between the two treatment strategies was not observed for progression-free survival, although radiotherapy was numerically favored...
Patients With Anaplastic Oligodendroglioma Identified Who May Benefit From Adjuvant PCV
5/31/2013
A further report on the results of EORTC trial 26951 indicates that CpG island methylator phenotype (CIMP) status and O 6-methylguanine-DNA methyltransferase (MGMT) promoter methylation as assessed by MGMT-STP27 are the most informative for identifying grade III glioma patients who might benefit from the addition of procarbazine, CCNU and vincristine (PCV) chemotherapy to radiation therapy...
Complication Risk After Breast Reconstruction Affected By Weight Of Tissue Flaps
5/31/2013
For women undergoing breast reconstruction after mastectomy, the weight of the tissue flap used affects the risk of an important complication called fat necrosis, reports a study in Plastic and Reconstruction Surgery-Global Open®, the official open-access medical journal of the American Society of Plastic Surgeons (ASPS)...
Previously Unidentified Cells Offer Potential Targets For Future Treatments Of Prostate Cancer
5/31/2013
Researchers have identified a sub-group of cells that could contribute to prostate cancer recurrence, opening up new ways to treat the disease, which claims more than 3000 lives a year in Australia. Published in Science Translational Medicine, a study led by Monash University researchers has found prostate cancer cells that survive androgen withdrawal treatment...
Radiation oncology research received 197 grants, totaling only 1.6 percent ($85.5 million) of the $5...
Scientists at The University of Nottingham have found that a genetic rogue element produced by sequences until recently considered 'junk DNA' could promote cancer progression...
Randomized Clinical Trials In Radiation Oncology Clinical Practice Of Great Value
5/31/2013
Cancer patients, physicians and insurers want to be sure that whatever therapy is recommended and provided to patients is based on evidence, preferably results from randomized clinical trials. But are there enough clinical trials data to provide this level of confidence? A University of North Carolina School of Medicine study says not necessarily...
New Method To Test Breast Lesions Could Better Detect Cancer, Save Money By Reducing Repeat Biopsies
5/31/2013
A newly developed, single-step Raman spectroscopy algorithm has the potential to simultaneously detect microcalcifications and enable diagnosis of the associated breast lesions with high precision, according to data published in Cancer Research, a journal of the American Association for Cancer Research. "Nearly 1...
Inflatable Leg Wraps Reduce Clot Risk After Stroke
5/31/2013
Stroke patients can reduce their risk of blood clots and death by using a compression device that wraps around their legs, according to new research published in The Lancet. For the first time, scientists have demonstrated that the likelihood of dying after stroke is lowered by gently squeezing the legs...
Two GSK Skin Cancer Drugs Approved By FDA
5/30/2013
Two new GlaxoSmithKline (GSK) drugs, Tafinlar (dabrafenib) and Mekinist (trametinib), have been approved for the treatment of patients with advanced melanoma by the U.S. Food and Drug Administration (FDA). Melanoma is the most dangerous form of skin cancer and the number one cause of death from skin disease...