Glycotope GmbH, a global leader in optimizing the sugar chains (glycosylation) of biopharmaceuticals, announced full details of first-in-man Phase I trial data for CetuGEXTM, an anti-epidermal growth factor receptor (EGFR) monoclonal antibody (mAb) with optimized and fully human glycosylation for a greatly enhanced anti-tumor activity and reduced side-effects...
Three out of 20 flexible gastrointestinal (GI) endoscopes used for screening were found to harbor unacceptable levels of "bio dirt" - cells and matter from a patient's body that could pose potential infection risk - according to a study of endoscopes used at five hospitals across the U.S...
VU Study Identifies New Mechanism For Cancer Development
6/11/2013
Researchers at Vanderbilt University Medical Center led by a 32-year-old postdoctoral fellow have discovered a new mechanism for the development of cancer that is challenging conventional scientific wisdom. Bhuminder Singh, Ph.D...
New Targets In Diverse Cancers Identified Via Clinical Sequencing Technology
6/11/2013
Novel abnormalities in the FGFR gene, called FGFR fusions, were identified in a spectrum of cancers, and preliminary results with cancer cells harboring FGFR fusions suggested that some patients with these cancers may benefit from treatment with FGFR inhibitor drugs, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research...
FDA Approves Scalp-Cooling For Chemo Hair Loss Final Trial
6/11/2013
Dignitana, a world leader in medical scalp-cooling technology, has announced that it has received U.S. Food and Drug Administration (FDA) approval for its Investigational Device Exemption (IDE) application and is now free to initiate a highly anticipated multi-center, pivotal trial of the patented DigniCap® System...
Potential Drug Target Identified For Treatment-Resistant Anemias
6/11/2013
Researchers at Whitehead Institute have identified a protein that is the target of glucocorticoids, the drugs that are used to increase red blood cell production in patients with certain types of anemia, including those resulting from trauma, sepsis, malaria, kidney dialysis, and chemotherapy...
CT Scans Associated With Increased Cancer Risk
6/11/2013
An analysis of seven healthcare systems in the U.S. has found that pediatric radiation exposure from CT scans can potentially double the risk of cancer caused by radiation. The study, published in the journal JAMA Pediatrics, revealed that the number of CT scans among young children has more than doubled from 1996 to 2005. Scans rose from about 330,000 in 1995 to 1...
Normal Version Of Molecular Pathway Affected In Poor-Prognosis Childhood Leukemia
6/11/2013
Through genetic engineering of laboratory models, researchers at Dartmouth-Hitchcock Norris Cotton Cancer Center have uncovered a vulnerability in the way cancer cells diverge from normal regenerating cells that may help treat children with leukemia as reported in the journal PNAS...
Vegetable Fats Reduce Prostate Cancer Death Risk
6/11/2013
Prostate cancer patients who replace animal fats and some carbohydrates with vegetable fats have a lower risk of premature death, researchers from the University of California reported in JAMA Internal Medicine. In the United States alone, nearly 2.5 million men currently live with prostate cancer...
In our daily lives, clutter is something that gets in our way, something that makes it harder for us to accomplish things. For doctors and scientists trying to parse mountains of raw biological data, clutter is more than a nuisance; it can stand in the way of figuring out how best to treat someone who is very sick...