Minimally Invasive Techniques Allow Doctors To Remove Suspicious Polyps, Keep Colon Intact
6/19/2013
Millions of people each year have polyps successfully removed during colonoscopies. But when a suspicious polyp is bigger than a marble or in a hard-to-reach location, patients are referred for surgery to remove a portion of their colon - even if doctors aren't sure whether the polyp is cancerous or not...
'Undruggable' To Druggable: A New Target For Cancer Drug Development
6/19/2013
Harvard Stem Cell Institute (HSCI) researchers have identified in the most aggressive forms of cancer a gene known to regulate embryonic stem cell self-renewal, beginning a creative search for a drug that can block its activity. The gene, SALL4, gives stem cells their ability to continue dividing as stem cells rather than becoming mature cells...
Protein Being Studied To Fight Cancer; May Cause Toxicity In Cardiac Cells
6/19/2013
A study by researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences and the Department of Pharmacology at the University of California, San Diego, shows that a protein called MCL-1, which promotes cell survival, is essential for normal heart function...
Whole Exome Sequencing Seeks Out Adenoid Cystic Carcinoma
6/19/2013
Adenoid cystic carcinoma (ACC) is a slow-growing and often fatal malignancy that can occur at multiple organ sites, but is most frequently found in the salivary glands. The primary treatment is surgical removal; however, the majority of patients develop metastatic disease...
Advanced Hormone-Sensitive Breast Cancer Responds To Osteoporosis Drug
6/19/2013
A new osteoporosis drug hinders the growth of estrogen-sensitive cancer that has become resistant to treatment with tamoxifen, a study in mice shows. The results were presented at The Endocrine Society's 95th Annual Meeting in San Francisco...
Blood Test May Detect Sexually Transmitted Throat Cancer
6/18/2013
A blood test can detect antibodies of HPV that can cause throat and oral cancers years before the symptoms of the disease become apparent, researchers from the National Cancer Institute and the International Agency for Research on Cancer reported in the Journal of Clinical Oncology...
Drug-Resistant Prostate Cancer Treated With New Medication In The Laboratory
6/18/2013
A new drug called pyrvinium pamoate inhibits aggressive forms of prostate cancer that are resistant to standard drugs, according to a study conducted in an animal model. The results were presented at The Endocrine Society's 95th Annual Meeting in San Francisco...
Discovery Of Source Of Tumor Growth In Aggressive Prostate Cancer
6/18/2013
Researchers have discovered a molecular switch that explains, at least in part, how some fast-growing prostate cancers become resistant to hormone treatment, a new study conducted in human cell cultures and mice finds. The results were presented at The Endocrine Society's 95th Annual Meeting in San Francisco...
Diabetes And Glucose Meters, Prostate Cancer Bone Metastases, Thyroid Autoimmunity And More
6/18/2013
Researchers from the Icahn School of Medicine at Mount Sinai are presenting several new studies at ENDO 2013, The Endocrine Society's Annual Meeting & Expo (ENDO) from June 15-18 in San Francisco...
Process Of Metastasis Explained By 'Chase And Run' Cell Movement Mechanism
6/18/2013
A mechanism that cells use to group together and move around the body - called 'chase and run' - has been described for the first time by scientists at UCL. Published in Nature Cell Biology, the new study focuses on the process that occurs when cancer cells interact with healthy cells in order to migrate around the body during metastasis...