Outcome Of Experimental Chlamydia Infections Points Towards Cancer
6/24/2013
Chlamydia trachomatis is a human pathogen that is the leading cause of bacterial sexually transmitted disease worldwide with more than 90 million new cases of genital infections occurring each year. About 70 percent of women infected with Chlamydia remain asymptomatic and these bacteria can establish chronic infections for months, or even years...
Researchers Discover How A Mutated Protein Outwits Evolution And Fuels Leukemia
6/24/2013
Scientists have discovered the survival secret to a genetic mutation that stokes leukemia cells, solving an evolutionary riddle and paving the way to a highly targeted therapy for leukemia. In a paper published in Cell, researchers at NYU Langone Medical Center describe how a mutated protein, called Fbxw7, behaves differently when expressed in cancer cells versus healthy cells...
Three Important Studies Published In The June Issue Of Neurosurgery
6/24/2013
The results of three important studies have been published in the June issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health...
Light And Nanoprobes Detect Early Signs Of Infection
6/24/2013
Duke University biomedical engineers and genome researchers have developed a proof-of-principle approach using light to detect infections before patients show symptoms. The approach was demonstrated in human samples, and researchers are now developing the technique for placement on a chip, which could provide fast, simple and reliable information about a patient...
Genetic Variants Identified That Predict Aggressive Prostate Cancers
6/23/2013
Researchers at Moffitt Cancer Center and colleagues at Louisiana State University have developed a method for identifying aggressive prostate cancers that require immediate therapy. It relies on understanding the genetic interaction between single nucleotide polymorphisms (SNPs). The goal is to better predict a prostate cancer's aggressiveness to avoid unnecessary radical treatment...
Ibrutinib Shows Surprising Efficacy As Treatment For Chronic Leukemia, Mantle Cell Lymphoma
6/23/2013
Two clinical studies published in the New England Journal of Medicine with an accompanying editorial suggest that the novel agent ibrutinib shows real potential as a safe, effective, targeted treatment for adults with chronic lymphocytic leukemia (CLL) and for patients with mantle cell lymphoma (MCL)...
No Danger Of Cancer Through Gene Therapy Virus
6/23/2013
In fall 2012, the European Medicines Agency (EMA) approved the modified adeno-associated virus AAV-LPL S447X as the first ever gene therapy for clinical use in the Western world...
Once-Abandoned Cancer Drug Class Offers Renewed Hope For Breast And Ovarian Cancer Treatment
6/23/2013
Could drugs that block the body's system for repairing damage to the genetic material DNA become a boon to health? As unlikely as it may seem, those compounds are sparking optimism as potential treatments for ovarian and breast cancers driven by a mutation in BRCA, a gene that made headlines when actress Angelina Jolie revealed she carries the mutation...
Chlamydia Infection May Pave Way For Cancer Via DNA Damage
6/22/2013
New research from Germany suggests that persistent infection by Chlamydia may pave the way for cancer: not only does the pathogen cause mutations in host cell DNA, it also inhibits the cellular mechanisms that attempt to repair the damage...
Low Sperm Linked To Cancer Risk
6/22/2013
Men who have no sperm have a higher risk of developing cancer than other males, researchers from Stanford University School of Medicine reported in Fertility and Sterility (June 20th, 2013 issue). When a man has no measurable level of sperm in his semen he has azoospermia, he is azoospermic...