Personalized risk calculator for women's cancers
7/31/2013
Researchers have discovered a new way of predicting whether a woman is at risk of cancer of the breast, ovaries, or uterus, according to a study published in the journal PLoS Medicine...
New understanding of actin filament growth in cells
7/30/2013
University of Oregon biochemists have determined how tiny synthetic molecules disrupt an important actin-related molecular machine in cells in one study and, in a second one, the crystal structure of that machine when bound to a natural inhibitor...
Singapore scientists discover new drug targets for aggressive breast cancer
7/30/2013
Scientists at A*STAR's Genome Institute of Singapore (GIS) led in a study that has identified genes that are potential targets for therapeutic drugs against aggressive breast cancer. These findings were reported in the July 2013 issue of PNAS. Out of the 1.5 million women diagnosed with breast cancer in the world annually, nearly one in seven of these is classified as triple negative...
Technique to create better anti-cancer agents, arthritis drugs, and more
7/30/2013
Many drugs such as agents for cancer or autoimmune diseases have nasty side effects because while they kill disease-causing cells, they also affect healthy cells. Now a new study has demonstrated a technique for developing more targeted drugs, by using molecular "robots" to hone in on more specific populations of cells...
No improvement seen in HIV-associated lymphoma survival during the antiretroviral therapy era
7/30/2013
Stable survival rates were observed for HIV-associated lymphoma patients during the antiretroviral therapy (ART) era in the US, according to a new study published in the Journal of the National Cancer Institute...
The slightest variation in a sequence of DNA can have profound effects. Modern genomics has shown that just one mutation can be the difference between successfully treating a disease and having it spread rampantly throughout the body...
New drug targets discovered for aggressive breast cancer
7/30/2013
Scientists at A*STAR's Genome Institute of Singapore (GIS) led in a study that has identified genes that are potential targets for therapeutic drugs against aggressive breast cancer. These findings were reported in the July 2013 issue of PNAS. Out of the 1.5 million women diagnosed with breast cancer in the world annually, nearly one in seven of these is classified as triple negative...
High platelet reactivity on clopidogrel predicts stent thrombosis, heart attack, and bleeding
7/30/2013
Patients who receive a drug-eluting stent (DES) and demonstrate high platelet reactivity on clopidogrel are more likely to have blood clots form on the stent and to suffer a heart attack; however, these patients are less likely to develop bleeding complications. One-year results of the ADAPT-DES trial was published online in The Lancet...
Screening asymptomatic high-risk adults for lung cancer may reduce deaths
7/29/2013
A systematic review of the evidence suggests that screening asymptomatic high-risk adults at risk for lung cancer using low-dose computed tomography (LDCT) may reduce mortality. Lung cancer is the third most common cancer in the United States and is the leading cause of cancer-related death for both men and women...
Both web-based and print-based decision aids appear to improve patients' informed decision making about prostate cancer screening up to 13 months later, but does not appear to affect actual screening rates, according to a study by Kathryn L. Taylor, Ph.D., of Georgetown University, Washington, D.C., and colleagues...