Among underserved patients whose colorectal cancer (CRC) screening was not up to date, mailed outreach invitations appear to result in higher CRC screening compared with usual care, according to a study by Samir Gupta, M.D., M.S.C.S., of the Veterans Affairs San Diego Healthcare System, and the University of California, San Diego, and colleagues...
Long-term calcium-channel blocker use for hypertension associated with higher breast cancer risk
8/05/2013
Long-term use of a calcium-channel blocker to treat hypertension (high blood pressure) is associated with higher breast cancer risk, according to a report published by JAMA Internal Medicine, a JAMA Network publication...
New drivers of glioblastoma
8/05/2013
Several genetic drivers of glioblastomas - malignant brain tumors - are reported in an article published online this week in Nature Genetics. These discoveries shed light on how these tumors develop and suggest possible treatment options for a subset of glioblastoma patients. Glioblastoma is difficult to treat and usually associated with poor clinical outcomes...
Tumor cell vaccination trial to promote anti-leukemia responses
8/05/2013
Chronic lymphocytic leukemia (CLL) is a cancer of the blood and bone marrow that most often affects older adults. CLL responds to bone marrow stem cell transplantation (allo-HSCT); however, the rate of relapse for CLL remains relatively high...
A study in the Journal of Biological Chemistry identifies a new therapeutic approach to treat prostate cancer. Conducted at Cincinnati Children's Hospital Medical Center, the research shows that expression of the FoxM1 protein is essential for prostate cancer to develop in mouse models. The study appears in the journal's Aug. 2 edition...
PET/CT bests gold standard bone marrow biopsy for diagnosis and prognosis of lymphoma patients
8/05/2013
A more precise method for determining bone marrow involvement in patients with diffuse large B-cell lymphoma (DLBCL) - a key factor in tailoring patient management plans - has been identified by researchers in a study published in the August issue of The Journal of Nuclear Medicine...
Deciphering the body's complex molecular pathways that lead to disease when they malfunction is highly challenging. Researchers at Sanford-Burnham Medical Research Institute now have a more complete picture of one particular pathway that can lead to cancer and diabetes...
Blocking sugar intake may reduce cancer risk or progression in obese and diabetic people
8/05/2013
Blocking dietary sugar and its activity in tumor cells may reduce cancer risk and progression, according to researchers from the Icahn School of Medicine...
Scientists at The University of Texas MD Anderson who identified a protein's dual role in cancer promotion have discovered a way to shut it down, opening a potential new avenue for cancer treatment...
Modeling of congenital amegakaryocytic thrombocytopenia using iPS cell technology
8/05/2013
A research group led by researcher Shinji Hirata and Professor Koji Eto at CiRA has conducted a study in which iPS cells generated from a patient with congenital amegakaryocytic thrombocytopenia (CAMT) were induced to differentiate into blood cells in vitro and then used to undertake a detailed study of the differences between these and cells from healthy subjects...