A team of scientists from the National Cancer Centre Singapore, Duke-NUS Graduate Medical School Singapore, and Taiwan's Chang Gung Memorial Hospital, LinKou, have made a breakthrough in understanding the cancer-promoting action of Aristolochic Acid (AA), a natural product of Aristolochia plants traditionally used in some Asian herbal remedies for weight loss and slimming...
Drugs that clog 'waste disposal' may treat aggressive breast cancers
8/14/2013
In a new paper in Cancer Cell, a team led by Judy Lieberman, PhD, of Boston Children's Hospital's Program in Cellular and Molecular Medicine reports "triple-negative" breast cancers may be vulnerable to drugs that attack the proteasome. This cellular structure acts as the cell's waste disposal, breaking down damaged or unneeded proteins...
Cervical cancer screening and treatment are neglected in low- and middle-income countries
8/13/2013
While there have been substantial improvements in mortality rates and an increase in access to reproductive health interventions in low- and middle-income countries (LMICs), the global health community is neglecting prevention, screening, and treatment for cervical cancer in LMICs...
Cervical cancer screening and treatment are neglected in low- and middle-income countries
8/13/2013
While there have been substantial improvements in mortality rates and an increase in access to reproductive health interventions in low- and middle-income countries (LMICs), the global health community is neglecting prevention, screening, and treatment for cervical cancer in LMICs...
Breast cancer drugs may be used to treat lung cancer
8/13/2013
Scientists have discovered that experimental drugs developed as treatments of ovarian and breast cancer could be used to treat lung cancer, according to a study published in the journal Oncogene...
Breast cancer drugs may be used to treat lung cancer
8/13/2013
Scientists have discovered that experimental drugs developed as treatments of ovarian and breast cancer could be used to treat lung cancer, according to a study published in the journal Oncogene...
Patients with advanced basal cell carcinoma who are not suitable for surgery or radiotherapy, could benefit from Erivedge (vismodegib) which is available following conditional EMA authorisation for use in the UK and listing on the national Cancer Drugs Fund (CDF)...
Making tumor-targeting T cells in a dish
8/13/2013
A method for producing from stem cells a large quantity of human immune cells capable of killing tumor cells in mice is presented in a paper published online this week in Nature Biotechnology. The approach may make it easier to implement cancer 'immunotherapies' - a suite of treatments that activate the immune system to attack tumors...
'Smart' nanoparticles designed to improve drug delivery, DNA self-assembly
8/13/2013
A team of chemists in SU's College of Arts and Scientists has used a temperature-sensitive polymer to regulate DNA interactions in both a DNA-mediated assembly system and a DNA-encoded drug-delivery system. Their findings, led by Associate Professor Mathew M...
Novel biological pathway leads to successful treatment of triple negative breast cancer
8/13/2013
Researchers at The Pennsylvania State University College of Medicine, led by Dr. Ian S. Zagon, have discovered that a novel biological pathway, the OGF-OGFr axis, can be modulated in human triple-negative breast cancer cells to inhibit proliferation. According to BreastCancer.org 1 in 8 women in the U.S. will develop invasive breast cancer and more than 39,000 deaths occur annually...