Researchers develop specific tests to identify cancer biomarkers in dermatomyositis
9/03/2013
Researchers from major universities in the U.S. have developed specific tests to identify cancer biomarkers in patients with dermatomyositis - a systemic inflammatory disease associated with increased risk of malignancy...
The mutation occurs in the androgen-synthesizing enzyme 3βHSD1 in castration-resistant prostate cancer (CRPC), according to research published online in Cell. This mutation enables the tumor to make its own supply of androgens, a hormone that fuels the growth of the prostate cancer. Prostate cancer requires a constant supply of androgens in order to sustain itself...
Highlights from the XV International Congress of Immunology, Milan
9/02/2013
New perspectives against transplant rejection New scientific results that could one day allow transplanted patients to avoid side effects caused by immunosuppressive therapy were presented at the International Congress of Immunology in Milan...
Susceptibility to prostate cancer increased by mutations in a gene that impacts immune function
9/02/2013
A team of researchers led by Janet Stanford, Ph.D., of Fred Hutchinson Cancer Research Center has discovered that mutations in the gene BTNL2, which encodes a protein involved in regulating T-cell proliferation and cytokine production - both of which impact immune function - increase the risk of developing prostate cancer...
The mutation occurs in the androgen-synthesizing enzyme 3βHSD1 in castration-resistant prostate cancer (CRPC), according to research published online in Cell. This mutation enables the tumor to make its own supply of androgens, a hormone that fuels the growth of the prostate cancer. Prostate cancer requires a constant supply of androgens in order to sustain itself...
New strategy against high-risk leukemia
9/02/2013
St. Jude Children's Research Hospital scientists have identified a protein that certain high-risk acute lymphoblastic leukemia (ALL) cells need to survive and have used that knowledge to fashion a more effective method of killing tumor cells. The findings appear in the journal Blood...
Breast cancer prognosis predicted by protein
9/02/2013
Researchers have identified a protein that they believe may help predict breast cancer prognosis, potentially relieving thousands of women at low risk from having to undergo painful, oft-debilitating therapies, while insuring the most successful treatments for those at high risk. The research was published ahead of print in the journal Molecular and Cellular Biology...
Drugs effective at preventing breast cancer metastasis in mouse model
9/02/2013
When a cancer cell sloughs off the edge of a tumor in the breast, it faces a tough road to survive. The cell must not only remain physically intact as it rushes through blood vessels, but it also must find a new organ to lodge itself in, take in enough nutrients and oxygen to stay alive, and begin dividing, all while escaping notice by the body's immune system...
Susceptibility to prostate cancer increased by mutations in a gene that impacts immune function
9/02/2013
A team of researchers led by Janet Stanford, Ph.D., of Fred Hutchinson Cancer Research Center has discovered that mutations in the gene BTNL2, which encodes a protein involved in regulating T-cell proliferation and cytokine production - both of which impact immune function - increase the risk of developing prostate cancer...
A prominent protein activated by inflammation is the key instigator that converts glioblastoma multiforme cells to their most aggressive, untreatable form and promotes resistance to radiation therapy, an international team lead by researchers at The University of Texas MD Anderson Cancer Center reported online today in the journal Cancer Cell...