New mutation identified, associated with better survival in lung cancer patients
9/16/2013
Japanese researchers have identified a mutation associated with a higher incidence of lung cancer in Japanese women who do not smoke, but better survival in lung cancer patients...
First randomized trial of targeted cancer medicine in all tumor types
9/16/2013
A further step along the road to the personalisation of cancer medicine, where treatment is based on the individual molecular characteristics of tumours rather than their primary site, was presented at the 2013 European Cancer Congress (ECC2013), which started on Friday 27 September in Amsterdam, The Netherlands...
Versatile microRNAs choke off cancer blood supply, suppress metastasis
9/15/2013
A family of microRNAs (miR-200) blocks cancer progression and metastasis by stifling a tumor's ability to weave new blood vessels to support itself, researchers at The University of Texas MD Anderson Cancer Center report in Nature Communications...
The protein Merlin "arranges" other protein interactions to control growth and prevent cancer
9/15/2013
Johns Hopkins researchers have figured out the specific job of a protein long implicated in tumors of the nervous system. Reporting on a new study described in the Sept...
Gene-expression-based biomarker predicts long-term risk of breast cancer recurrence
9/15/2013
A comparison of three methods of predicting the risk of recurrence in women treated for estrogen-receptor (ER)-positive breast cancer finds that only the breast cancer index (BCI) - a biomarker based on the expression levels of seven tumor-specific genes - accurately identifies patients who continue to be at risk after five years of treatment with either tamoxifen or the arom...
Drug treatment means better, less costly care for children with sickle cell disease
9/15/2013
The benefits of hydroxyurea treatment in people with sickle cell disease are well known - fewer painful episodes, fewer blood transfusions and fewer hospitalizations. Now new research from the Johns Hopkins Children's Center and other institutions reveals that by preventing such complications, the drug can also considerably lower the overall cost of medical care in children with this condition...
Brachytherapy to treat cervical cancer declines in US, treatment associated with higher survival
9/14/2013
A study by researchers at Brigham and Women's Hospital (BWH) found that brachytherapy treatment was associated with better cause-specific survival and overall survival in women with cervical cancer. The population-based analysis also revealed geographic disparities and decline in brachytherapy treatment in the United States...
Brachytherapy to treat cervical cancer declines in US, treatment associated with higher survival
9/14/2013
A study by researchers at Brigham and Women's Hospital (BWH) found that brachytherapy treatment was associated with better cause-specific survival and overall survival in women with cervical cancer. The population-based analysis also revealed geographic disparities and decline in brachytherapy treatment in the United States...
Discovery of cell division 'master controller' may improve understanding and treatment of cancer
9/14/2013
In a study to be published in the journal Nature, two Dartmouth researchers have found that the protein cyclin A plays an important but previously unknown role in the cell division process, acting as a master controller to ensure the faithful segregation of chromosomes during cell division. Cell division is the process in which cells reproduce by splitting into two identical copies...
Radiotherapy in girls and the risk of breast cancer later in life
9/14/2013
Exposing young women and girls under the age of 20 to ionizing radiation can substantially raise the risk of their developing breast cancer later in life. Scientists may now know why. A collaborative study, in which Berkeley Lab researchers played a pivotal role, points to increased stem cell self-renewal and subsequent mammary stem cell enrichment as the culprits...