Life or death for cells could hinge on a protein
9/20/2013
Each cell in an organism has a sensor that measures the health of its "internal" environment. This "alarm" is found in the endoplasmic reticulum (ER), which is able to sense cellular stress and trigger either rescue responses or the death of the cell...
New technology presented at OSA's Frontiers in Optics meeting will help fight cancer
9/20/2013
Scientists seeking new ways to fight cancer often try to understand the subtle, often invisible, changes to DNA, proteins, cells, and tissue that alter the body's normal biology and cause disease. Now, to aid in that fight, a team of researchers has developed a sophisticated new optical imaging tool that enables scientists to look deep within tumors and uncover their inner workings...
Diversity of microbial growth strategies in a limited nutrient world
9/20/2013
The budding yeast, Saccharomyces cerevisiae, is a prime organism for studying fundamental cellular processes, with the functions of many proteins important in the cell cycle and signaling networks found in human biology having first been discovered in yeast...
New technique speeds up cancer diagnosis during surgery
9/20/2013
Tissue-conserving cancer surgery is a highly skilled procedure which involves time-consuming tissue preparation to detect the margins of cancerous tissue. The goal is to remove as much of the tumour as possible while sparing healthy tissue...
Shorter radiotherapy for early breast cancer 'best option'
9/20/2013
Results from a 10-year study confirm that giving radiotherapy to women with early breast cancer in a lower overall dose through fewer, higher doses is at least as effective and safe as the current standard of a higher overall dose. The finding comes from the UK Standardisation of Breast Radiotherapy (START) trials, results of which were recently published in The Lancet Oncology...
Boehringer Ingelheim Pharmaceuticals, Inc. have announced the FDA has granted Breakthrough Therapy designation to volasertib*, an investigational inhibitor of polo-like kinase (Plk), being evaluated for the treatment of patients aged 65 or older with previously untreated acute myeloid leukemia (AML), ineligible for intensive remission induction therapy...
Discovery of potent tumor-suppressor in lung cancer
9/19/2013
New research shows that microRNA-486 is a potent tumor-suppressor molecule in lung cancer, and that the it helps regulate the proliferation and migration of lung-cancer cells, and the induction of programmed cell death, or apoptosis, in those cells. The preclinical study was led by researchers at the Ohio State University Comprehensive Cancer Center - Arthur G...
Boehringer Ingelheim Pharmaceuticals, Inc. have announced the FDA has granted Breakthrough Therapy designation to volasertib*, an investigational inhibitor of polo-like kinase (Plk), being evaluated for the treatment of patients aged 65 or older with previously untreated acute myeloid leukemia (AML), ineligible for intensive remission induction therapy...
Fragile X syndrome protein linked to breast cancer progression
9/19/2013
Claudia Bagni*, has identified the way Fragile X Mental Retardation Protein or FMRP contributes to the progression of breast cancer. For this research the group of Bagni collaborated with colleagues from the VIB/KU Leuven departments of Bart De Strooper and Peter Carmeliet**, with Patrick Neven*** and with several research centers and Hospitals in Italy and the UK...
Possible antidote discovered for tamoxifen-related mental fog
9/19/2013
A team from the University of Rochester Medical Center has shown scientifically what many women report anecdotally: that the breast cancer drug tamoxifen is toxic to cells of the brain and central nervous system, producing mental fogginess similar to "chemo brain...