Structure of active coagulation factor XIII published - milestone on the way to safe anticoagulation
10/16/2013
Zedira, in cooperation with the group of Prof. Gerhard Klebe in Marburg, reported the first crystal structure of coagulation factor XIII in the active conformation. The article is now published in Angewandte Chemie International Edition and provides a proprietary high-resolution structure of FXIIIa in complex with the inhibitor ZED1301 serving as lead structure...
New breast cancer imaging 'detects subtypes and early treatment repsonse'
10/16/2013
Researchers say that a new imaging technique tested on mice is able to identify breast cancer subtypes accurately, as well as detecting early treatment response. This is according to a new study published in the journal Cancer Research...
DNA scanning technology leads to new library of cancer targets
10/16/2013
More patients than ever stand to benefit from a promising new type of cancer treatment, after scientists compiled a library of molecules that can prime patients' immune systems to fight a range of cancers including leukaemia, myeloma, lung cancer and skin cancer...
The EMA's Pharmacovigilance Risk Assessment Committee (PRAC) has completed its review of HES solutions following an assessment of new information and commitments from companies for additional studies and risk minimisation activities...
Structure of active coagulation factor XIII published - milestone on the way to safe anticoagulation
10/16/2013
Zedira, in cooperation with the group of Prof. Gerhard Klebe in Marburg, reported the first crystal structure of coagulation factor XIII in the active conformation. The article is now published in Angewandte Chemie International Edition and provides a proprietary high-resolution structure of FXIIIa in complex with the inhibitor ZED1301 serving as lead structure...
New evidence that aging tumor cells may be an effective cancer treatment
10/16/2013
Scientists at the University of Massachusetts Medical School have shown that diffuse large B-cell lymphoma (DLBCL) may be susceptible to treatment by re-activating the normal aging program in tumor cells so they can no longer divide...
Barriers to HPV vaccination
10/16/2013
A new study explores why girls in minority groups and low-income families, who are most at risk for cervical cancer, may not be getting the human papillomavirus or HPV vaccine...
Link suggested between nervous system, certain thyroid cancers
10/16/2013
A specific protein once thought to exist only in the brain may play a crucial role in a deadly form of thyroid cancer, as well as other cancers, and provide a fresh target for researchers seeking ways to stop its progression, UT Southwestern Medical Center researchers report in Cancer Cell...
New approach may improve personalized cancer treatments
10/16/2013
Researchers from the University of Minnesota, Mayo Clinic, and University of Toronto have successfully shown that a new method for targeting mutated cells could create a major breakthrough in a personalized medicine approach to treat cancer. The team's findings are published in Cancer Research, a journal of the American Association of Cancer Research...
New breast cancer imaging 'detects subtypes and early treatment repsonse'
10/16/2013
Researchers say that a new imaging technique tested on mice is able to identify breast cancer subtypes accurately, as well as detecting early treatment response. This is according to a new study published in the journal Cancer Research...