Researcher says Skid Row cancer study has implications for treatment today
10/22/2013
An ethically dubious medical research study from the 1950s and 60s, known as the "Bowery series," foreshadowed and shared commonalities with prostate cancer screening and treatment measures as they are carried out today, argues University of Pennsylvania physician and historian Robert Aronowitz in two new publications...
One of the challenges of understanding cancer is trying to determine the mechanisms that drive metastasis, or the process by which tumor cells are able to spread throughout the body. In order to investigate metastasis, researchers at The Wistar Institute focused on a process involving the phenotypes - the outward, physical appearance based on genetic coding - of tumor cells...
The X chromosome often affected by mutations in cancer
10/22/2013
Every case of cancer originates from changes in a person's genetic material (mutations). These usually occur as "somatic mutations" in individual cells during an individual's lifetime, rather than being inherited from a person's parents. "Over time, the original damaged cell accumulates additional mutations, and it is still largely unknown why," says Prof...
Traffic-related air pollution a substantial public health concern
10/21/2013
Traffic-related air pollution is increasingly shown to have negative health effects according to a growing body of epidemiologic evidence and is a substantial public health concern in Canada, argues a commentary published in CMAJ (Canadian Medical Association Journal)...
Biological clock: breast tissue ages faster than body
10/21/2013
A study that could provide us with a better understanding of cancer and stem cell research uncovers a biological clock in our genomes that affects how our bodies age. And a surprising finding reveals that the tissue in women's breasts is biologically older than the rest of the body...
Traffic-related air pollution a substantial public health concern
10/21/2013
Traffic-related air pollution is increasingly shown to have negative health effects according to a growing body of epidemiologic evidence and is a substantial public health concern in Canada, argues a commentary published in CMAJ (Canadian Medical Association Journal)...
Biological clock: breast tissue ages faster than body
10/21/2013
A study that could provide us with a better understanding of cancer and stem cell research uncovers a biological clock in our genomes that affects how our bodies age. And a surprising finding reveals that the tissue in women's breasts is biologically older than the rest of the body...
Rapid increase in use of novel oral anticoagulants in very elderly patients under scrutiny
10/21/2013
The use of novel oral anticoagulants (NOACs) has increased rapidly in Ontario, Canada, especially in people aged 85 years and over, in the 2 years since the drugs were approved for use in patients with atrial fibrillation (AF), according to new research published in CMAJ Open...
Treatment of ovarian cancer may be improved by nanotech system, cellular heating
10/21/2013
The combination of heat, chemotherapeutic drugs and an innovative delivery system based on nanotechnology may significantly improve the treatment of ovarian cancer while reducing side effects from toxic drugs, researchers at Oregon State University report in a new study...
Rapid increase in use of novel oral anticoagulants in very elderly patients under scrutiny
10/21/2013
The use of novel oral anticoagulants (NOACs) has increased rapidly in Ontario, Canada, especially in people aged 85 years and over, in the 2 years since the drugs were approved for use in patients with atrial fibrillation (AF), according to new research published in CMAJ Open...