Discovery of protein factories may lead to novel agents for the treatment of cancer
10/27/2013
For 10 years, Patrick Cramer and his colleagues at Ludwig-Maximilians-Universitaet (LMU) in Munich have probed the structure of RNA polymerase I, a crucial cog in the machinery of all cells. Now they unveil the full three-dimensional conformation of the enzyme - at atomic resolution...
Effectiveness of clot-buster enhanced by ultrasound device in stroke patients
10/27/2013
A study led by researchers at The University of Texas Health Science Center at Houston (UTHealth) showed that a hands-free ultrasound device combined with a clot-busting drug was safe for ischemic stroke patients. The results of the phase II pilot study were reported in the American Heart Association journal Stroke. Lead author is Andrew D. Barreto, M.D...
Detecting ERG gene deletion may be useful for risk stratification in childhood ALL
10/27/2013
Results of EORTC trial 58951 suggest that detecting ERG gene deletion at diagnosis of childhood B-cell precursor (BCP) acute lymphoblastic leukemia (ALL) would be useful for risk stratification. The study, published in Leukemia showed that patients with the ERG gene deletion had a very good outcome with an 8-year event-free survival of 86.4% and an overall survival of 95.6%...
Discovery of protein factories may lead to novel agents for the treatment of cancer
10/27/2013
For 10 years, Patrick Cramer and his colleagues at Ludwig-Maximilians-Universitaet (LMU) in Munich have probed the structure of RNA polymerase I, a crucial cog in the machinery of all cells. Now they unveil the full three-dimensional conformation of the enzyme - at atomic resolution...
Effectiveness of clot-buster enhanced by ultrasound device in stroke patients
10/27/2013
A study led by researchers at The University of Texas Health Science Center at Houston (UTHealth) showed that a hands-free ultrasound device combined with a clot-busting drug was safe for ischemic stroke patients. The results of the phase II pilot study were reported in the American Heart Association journal Stroke. Lead author is Andrew D. Barreto, M.D...
Tumor factors that block muscle repair offer partial explanation for cancer wasting
10/26/2013
A new study reveals that tumors release factors into the bloodstream that inhibit the repair of damaged muscle fibers, and that this contributes to muscle loss during cancer wasting. The condition, also called cancer cachexia, accompanies certain types of cancer, causes life-threatening loss of body weight and lean muscle mass, and is responsible for up to one-in-four cancer deaths...
Drug-resistant breast tumors' defenses lowered by stealth nanoparticles
10/26/2013
Some of the most dangerous cancers are those that can outmaneuver the very drugs designed to defeat them, but researchers are now reporting a new Trojan-horse approach...
Tumor factors that block muscle repair offer partial explanation for cancer wasting
10/26/2013
A new study reveals that tumors release factors into the bloodstream that inhibit the repair of damaged muscle fibers, and that this contributes to muscle loss during cancer wasting. The condition, also called cancer cachexia, accompanies certain types of cancer, causes life-threatening loss of body weight and lean muscle mass, and is responsible for up to one-in-four cancer deaths...
Drug-resistant breast tumors' defenses lowered by stealth nanoparticles
10/26/2013
Some of the most dangerous cancers are those that can outmaneuver the very drugs designed to defeat them, but researchers are now reporting a new Trojan-horse approach...
Colorectal cancer: current screening guidelines 'may lead to missed diagnoses'
10/25/2013
Up to 10% of colorectal cancers could be missed by current screening programs of people who have a family history of colon polyps. This is according to a study published in the journal Cancer. Colorectal cancer (CRC) is the third leading cause of cancer-related death in the US according to the American Cancer Society. They estimate it will cause around 50,830 deaths this year...