NCI News
NCI study provides genetic insights into osteosarcoma in children
3/19/2020
A new study offers insight into genetic alterations associated with osteosarcoma, the most common bone tumor of children and adolescents, and the findings have implications for genetic testing of children with osteosarcoma and their families.
In NIH trial, selumetinib shrinks tumors, provides clinical benefit for children with NF1
3/18/2020
An NCI clinical trial finds the drug selumetinib improves outcomes for children with neurofibromatosis type 1 (NF1), shrinking inoperable tumors called plexiform neurofibromas, reducing pain, and improving function and overall quality of life.
Annual Report to the Nation: Cancer death rates continue to decline
3/12/2020
The 2020 Annual Report to the Nation on the Status of Cancer finds overall cancer death rates continue to decline in the United States for all cancer sites combined. A companion study looked at Healthy People 2020 targets for four common cancers.
Testing with combined biopsy method improves prostate cancer diagnosis in NCI study
3/04/2020
Testing for prostate cancer with a combined biopsy method led to more accurate diagnosis and prediction of the course of the disease in an NCI study. The method is poised to reduce the risk of prostate cancer overtreatment and undertreatment.
Immunotherapy drug improves outcomes for some children with relapsed leukemia
12/10/2019
For children and young adults with certain relapsed B-cell acute lymphoblastic leukemia (B-ALL), the immunotherapy drug blinatumomab is superior to standard chemotherapy, an NCI-sponsored Children’s Oncology Group trial shows.
Study quantifies impact of NCI-sponsored trials on clinical cancer care
9/18/2019
Nearly half of phase 3 cancer clinical trials carried out by the NCI-sponsored SWOG Cancer Research Network were associated with clinical care guidelines or new drug approvals, a study in JAMA Network Open shows.
Findings from a new NCI study of patients who received radioactive iodine (RAI) treatment for hyperthyroidism show an association between the dose of treatment and long-term risk of death from solid cancers, including breast cancer.
The 2019 Annual Report to the Nation on the Status of Cancer finds overall cancer death rates continue to decline and cancer incidence dropped in men and remained stable in women. A special section reports on recent cancer trends in younger adults.
Study shows incidence rates of aggressive subtypes of uterine cancer rising
5/22/2019
An NCI-led study shows rates for aggressive subtypes of uterine cancer rose rapidly among women ages 30 to 79 from 2000–2015. The findings, published in the Journal of Clinical Oncology, also reveal racial disparities in incidence and survival rates.
Harnessing T-cell “stemness” could enhance cancer immunotherapy
3/28/2019
A new study provides insight into how cancer immunotherapy works and suggests ways to enhance the treatment’s effectiveness. The NCI-led study, published in Science, examined the effect of high potassium levels on T cells.