NCI News
From 1999—2019, US rates of cancer death fell among Black people. Yet, in 2019, their rates remained higher than those of other racial and ethnic groups.
Uterine cancer deaths are rising in the United States, and are highest among Black women
5/05/2022
Deaths from uterine cancer are rising in the United States, and are highest among non-Hispanic Black women, according to a new study led by researchers at NCI, part of the National Institutes of Health. The higher death rates are related to the rising incidence of aggressive subtypes of uterine cancer.
Norman Sharpless steps down as director of the National Cancer Institute
4/04/2022
Norman E. “Ned” Sharpless, M.D., announces his decision to step down as NCI director, a position he has held since 2017. NCI Principal Deputy Director Douglas R. Lowy, M.D., will serve as NCI’s acting director beginning April 30, 2022.
NCI launches program to offer molecular characterization of childhood cancers
3/21/2022
The Molecular Characterization Initiative will offer state-of-the-art diagnoses to children, adolescents, and young adults with central nervous system tumors.
NCI researchers have found unique expression profiles in 50 genes that help identify rare anti-tumor lymphocytes that can infiltrate and help defeat metastatic solid epithelial tumors.
NCI study advances personalized immunotherapy for metastatic breast cancer
2/01/2022
NCI researchers have shown that an experimental form of immunotherapy that uses an individual’s own tumor-fighting immune cells could potentially be used to treat people with metastatic breast cancer who have exhausted all other treatment options.
A high-fiber diet may improve the response of melanoma patients to immunotherapy
12/23/2021
NCI researchers have found that a diet rich in fiber may help some people being treated for melanoma respond to immunotherapy treatment by influencing the gut microbiome. The new findings come from an analysis of people with melanoma and mouse models of the disease.
Drug combination helps children with acute promyelocytic leukemia avoid conventional chemotherapy
11/11/2021
A Children’s Oncology Group trial shows that the combination of all-trans retinoic acid and arsenic trioxide is highly effective in children with acute promyelocytic leukemia. The therapy avoids or minimizes the use of conventional chemotherapy.
Ibrutinib improves survival for younger people with diffuse large B-cell lymphoma
11/04/2021
NCI researchers have found that adding the targeted therapy ibrutinib (Imbruvica) to standard chemotherapy can improve how long some younger people with a specific form of diffuse large B-cell lymphoma live. The new findings come from a new analysis of a previously conducted phase 3 clinical trial called Phoenix.
Ibrutinib improves survival for younger people with diffuse large B-cell lymphoma
11/04/2021
NCI researchers have found that adding the targeted therapy ibrutinib (Imbruvica) to standard chemotherapy can improve how long some younger people with a specific form of diffuse large B-cell lymphoma live. The new findings come from a new analysis of a previously conducted phase 3 clinical trial called Phoenix.