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NCI News

NCI study highlights pandemic’s disproportionate impact on Black, American Indian/Alaska Native, and Latino adults

A large surveillance study led by NCI researchers suggests that the global COVID-19 pandemic has caused more deaths in the United States among Black, American Indian/Alaska Native, and Latino individuals than among white or Asian individuals.

NIH study illuminates origins of lung cancer in never smokers

NCI scientists and their international collaborators have found that the majority of lung cancers in never smokers arise when mutations caused by natural processes in the body accumulate. They also identified three subtypes of lung cancer these individuals.

In a common genetic disorder, blood test reveals when benign tumors turn cancerous

NCI scientists have developed a blood test that could one day offer a highly sensitive and inexpensive approach to detect cancer early in people with NF1. The blood test could also help doctors monitor how well patients are responding to treatment for their cancer.

Annual Report to the Nation: Rapid decrease in lung cancer and melanoma deaths lead overall continued decline in cancer death rate

The 2021 Annual Report to the Nation on the Status of Cancer finds overall cancer death rates continue to decline in the United States for all cancer sites combined. The rapid drop in lung cancer and melanoma deaths led to the overall decline.

International study of rare childhood cancer finds genetic clues, potential for tailored therapy

A team of international researchers has identified mutations in several genes, including TP53, MYOD1, and CDKN2A, that appear to be associated with an aggressive form of rhabdomyosarcoma in children. The findings could lead to more targeted treatments for the disease.

International research teams explore genetic effects of Chernobyl radiation

One study examined whether genetic changes associated with exposure to radiation from the 1986 accident were passed from parent to child. A second study documented the genetic changes in thyroid tumors from people exposed as children or fetuses to radiation from the accident.

Engineered immune cells deliver anticancer signal, prevent cancer from spreading

In an NCI study, treating mice with engineered immune cells shrank tumors and prevented the cancer from spreading to other parts of the body. The immunotherapy approach shows promise as a potential treatment for metastatic cancer.

NCI statement on ending structural racism in biomedical research

Statement from the National Cancer Institute in support of the NIH UNITE initiative to end structural racism in biomedical research. NCI Director Dr. Norman Sharpless describes NCI’s equity and inclusion efforts.

NCI study finds that people with SARS-CoV-2 antibodies may have a low risk of future infection

A prior infection with SARS-CoV-2, the virus that causes COVID-19, appears to protect, at least for a few months, against reinfection from the virus, according to an NCI study. The finding may have important public health implications.

Fecal microbiota transplants help patients with advanced melanoma respond to immunotherapy

For patients with cancers that do not respond to immunotherapy drugs, the use of fecal transplants to modify the gut microbiome may help some of these patients respond to the immunotherapy drugs.