Disease & Drug Information

Glossary of Terms

yttrium Y 90 DOTA monoclonal antibody HuAFP31

listen (IH-tree-um MAH-noh-KLOH-nul AN-tee-BAH-dee ) A substance being studied in the treatment of liver cancer. HuAFP31 is a monoclonal antibody that can bind to tumor cells that make a protein called alpha fetoprotein (AFP). It is linked to a radioactive substance called yttrium Y 90, which may help kill the cancer cells. Yttrium Y 90 DOTA monoclonal antibody HuAFP31 is a type of radioimmunoconjugate.

yttrium Y 90 DOTA monoclonal antibody HuPAM4

listen (IH-tree-um ... MAH-noh-KLOH-nul AN-tee-BAH-dee ...) A substance being studied in the treatment of advanced pancreatic cancer. Yttrium Y 90 DOTA monoclonal antibody HuPAM4 contains a monoclonal antibody that binds to a protein called MUC-1, which is found on some pancreatic cancer cells. It also contains a radioactive substance called yttrium Y 90, which may help kill cancer cells. Yttrium Y 90 DOTA monoclonal antibody HuPAM4 is a type of radioimmunoconjugate. Also called yttrium Y 90 clivatuzumab tetraxetan.

yttrium Y 90 DOTA-biotin

listen (IH-tree-um ... BY-oh-tin) A compound that contains the radioisotope yttrium Y 90 linked to the chemical biotin. Biotin is a molecule that binds strongly to the chemical streptavidin. Yttrium Y 90 DOTA-biotin will find tumor cells in the body that have been targeted by an antibody linked to streptavidin and kill them. It is being studied together with CC49-streptavidin in the treatment of cancer. Also called 90Y-DOTA-biotin.

yttrium Y 90 DOTA-tyr3-octreotide

listen (IH-tree-um ... ok-TREE-oh-tide) A substance being studied in the treatment of some types of cancer. Yttrium Y 90 DOTA-tyr3-octreotide contains a molecule that binds to a protein found on certain types of neuroendocrine tumors (tumors that form from cells that release hormones). It also contains a radioactive substance called yttrium Y 90, which may help kill cancer cells. Yttrium Y 90 DOTA-tyr3-octreotide is a type of radioconjugate. Also called yttrium Y 90 edotreotide and yttrium Y 90 SMT 487.

yttrium Y 90 edotreotide

listen (IH-tree-um ... eh-doh-TREE-oh-tide) A substance being studied in the treatment of some types of cancer. Yttrium Y 90 edotreotide contains a molecule that binds to a protein found on certain types of neuroendocrine tumors (tumors that form from cells that release hormones). It also contains a radioactive substance called yttrium Y 90, which may help kill cancer cells. Yttrium Y 90 edotreotide is a type of radioconjugate. Also called yttrium Y 90 DOTA-tyr3-octreotide and yttrium Y 90 SMT 487.

yttrium Y 90 epratuzumab tetraxetan

listen (IH-tree-um eh-pruh-TOO-zoo-mab teh-TRAK-seh-tan) A substance being studied in the treatment of certain types of B-cell cancer. Epratuzumab is a monoclonal antibody that binds to a protein called CD22, which is found on the surface of B cells. It is linked to a radioactive substance called yttrium Y 90, which may help kill cancer cells. Yttrium Y 90 epratuzumab tetraxetan is a type of radioimmunoconjugate.

yttrium Y 90 ibritumomab tiuxetan

listen (IH-tree-um ... ih-brih-TOO-moh-mab ty-UK-seh-tan) A drug used with the drug rituximab to treat certain types of B-cell non-Hodgkin lymphoma. It is also being studied in the treatment of other types of B-cell tumors. Yttrium Y 90 ibritumomab tiuxetan contains a monoclonal antibody that binds to a protein called CD20, which is found on B cells. It also contains a radioactive substance called yttrium Y 90, which may help kill cancer cells. Yttrium Y 90 ibritumomab tiuxetan is a type of radioimmunoconjugate. Also called IDEC-Y2B8, Y 90 ibritumomab tiuxetan, and Y 90 Zevalin.

yttrium Y 90 SMT 487

listen (IH-tree-um ) A substance being studied in the treatment of some types of cancer. Yttrium Y 90 SMT 487 contains a molecule that binds to a protein found on certain types of neuroendocrine tumors (tumors that form from cells that release hormones). It also contains a radioactive substance called yttrium Y 90, which may help kill cancer cells. Yttrium Y 90 SMT 487 is a type of radioconjugate. Also called yttrium Y 90 DOTA-tyr3-octreotide and yttrium Y 90 edotreotide.

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